KIRISH ............................................................................................................... 4
I – BOB. SON SUYAGI BOSHCHASINI ASEPTIK NEKROZINING
COVID - 19 O‘TKAZGAN BEMORLARDA KLINIK VA
PATOMORFOLOGIK O‘ZGARISHLARI ..................................................... 16
§1.1.COVID-19 da son suyagi boshchasini aseptik nekrozi yosh davrlardagi
(yoshlik, o‗smirlik, keksalik) rivojlanishi .............................................................. 16
§1.2 Son suyagi boshchasini avaskulyar nekrozining etiologiyasi va
patomorfologik o‗zgarishlari (Covid-19)............................................................... 25
§1.3. COVID -19 da son suyagi boshchasi aseptik nekrozining kortikoidlar
ta‘siridagi klinik-morfofunksional holati ............................................................... 27
§1.4. Ilmiy adabiyotlar tahlili buyicha umumiy xulosa .......................................... 34
II – BOB. TADQIQOTDA FOYDALANILGAN MATERIAL
VA USULLAR .................................................................................................. 38
§2.1.Jarrohlikda olingan son suyak boshchasining (makroskopik) tashqi
ko‗rinishini o‗rganish. ........................................................................................... 39
§2.2.Suyak to‗qimasini mikroskopik tekshiruvga tayyorlash................................. 40
§2.3. Morfometrik tekshiruvlar ............................................................................. 41
III – BOB. XUSUSIY MA’LUMOTLAR. COVID-19 INFEKSIYASI
ASORATI SIFATIDA SON SUYAK BOSHCHASI ASEPTIK NEKROZI
BILAN KASALLANGANLAR KLINIK-ANAMNESTIK
MA’LUMOTLARI ........................................................................................... 43
§3.1. Materialning klinik - morfologik tahlili ........................................................ 43
§3.2.Magnit rezonansli tomografiya tekshiruvini tahlili ........................................ 50
§3.3.Klinik-morfologik tekshiruv natijalari ..................................................... 53
3
IV – BOB. SON SUYAK BOSHCHASI ASEPTIK NEKROZINING
PATOGENEZI, MORFOGENEZI VA PATOMORFOLOGIK
MA’LUMOTLARI ........................................................................................... 57
§4.1. Son suyak boshchasi aseptik nekrozi patogenetik angiogen omilining
patomorfologik o‗zgarishlari ................................................................................. 57
§4.2. Son suyak boshchasi aseptik nekrozi patogenetik angiogen omilining
gistokimyoviy o‗zgarishlari ................................................................................... 64
§4.3. Son suyak boshchasi aseptik nekrozining makroskopik xarakteristikasi ....... 73
§4.4. COVID-19 infeksiyasi ta'sirida son suyak boshchasi aseptik nekrozi
rivojlanish dinamikasida yumshoq va qattiq to‗qimalardagi patomorfologik
o‗zgarishlar ........................................................................................................... 77
V-BOB. SON SUYAGI BOSHCHASI ASEPTIK NEKROZIDA
RIVOJLANADIGAN MORFOMETRIK KO‘RSATKICHLAR .................... 92
XOTIMA ........................................................................................................ 102
XULOSALAR ................................................................................................. 110
AMALIY TAVSIYALAR ............................................................................... 111
SHARTLI BELGILAR VA ATAMALAR ROʼYXATI ................................. 112
FOYDANILGAN ADABIYOTLAR RO‘YXATI: ......................................... 113
