QISQARTMALAR RO'YXATI
4
KIRISH........................................................................................................................ 6
I BOB. ADABIYOTLAR TAHLILI....................................................................16
§1.1. Ayollardagi kasalliklami rivojlanishida menopauzal davming roli.......... 16
§1.2. Kardioimmunologiya: yurak kasalliklari va gomeostazda immun tizim....21
1.2.1. Yurak qon tomir kasal liklarida immun tizimi..........................................21
§ 1.3. Menopauzani immun keksayish va yurak qon-tomir kasalliklarini
rivojlanishiga ta’siri.................................................................................................27
1.3.1. Limfotsitlar funksiyasiga tuxumdonlar steroidlarining ta’sir
mexanizmlari........................................................................................................27
1.3.2. Immun tizim qarishi.................................................................................. 30
1.3.3. Immun hujayralar soniga menopauzaning ta’siri.................................... 32
1.3.4. Sitokinlar darajasi va menopauza mahsulotlari hamda gormonal
davolash modulyatsiyasi..................................................................................... 34
§ 1.4. Menopauzal gormonal davolash va yurak qon-tomir kasalliklarining xavf
omillari.................................................................................................................... 37
§1.5. Profilaktik o‘rin bosuvchi gormonal davolash va endokrin gomeostazdagi
siljishlar................................................................................................................... 43
II BOB. TADQIQOT MATERIALLARI VA USULLARI.............................48
§2.1. Tadqiqot materiallari..................................................................................... 48
§2.2. Tadqiqot usullari........................................................................................... 49
§2.3. Olingan ma’lumotlami statistik tahlili......................................................... 57
III BOB. SHAXSIY TEKSHIRISH NATIJALARI.........................................58
§3.1. Klimakterik davrdagi og‘irlik darajasiga bog‘liq xolda ayollarda YUIK
klinik kechishining o‘ziga xos xususiyatlari......................................................... 58
§3.2. Menopauzal davrdagi ayollar o‘rtasidagi yurak ishemik kasalligi bor
bemorlarda gormonal gomeostazni klinik tekshirish natijalari............................64
§3.3. Menopauzal davrdagi bemorlarda yurak ishemik kasalligini klinik
kechishiga xavf omillarining ta’siri.......................................................................66
§3.4. Tekshirilgan guruhlarda lipid spektrining holati va menopauzal davrdagi
ayollarda yurak ishemik kasalligi destabilizatsiyasini rivojlanishida xavfni
bashoratlash uchun ulaming tashxislovchi ahamiyati...........................................78
§3.5. Menopauzal davrda ayollarda yurak ishemik kasalligini kechishiga klinik,
biokimyoviy, immun, gormonal xavf omillarini ta’siri........................................84
XOTIMA..................................................................................................................97
XULOSA................................................................................................................. 102
AMALIY TAVSIYALAR....................................................................................104
FOYDALANILGAN ADABIYOTLAR RO‘YXATI.....................................105
